Isler was born in the city of Valencia, but has studied and lived in Maracay since she was a little girl. She holds a BA in Management and Marketing. She has Swiss and German descent and also holds Swiss citizenship due to her Swiss grandfather from Lausanne.At age of 14 she started modeling as a way to cheer her mother and grandmother up after her aunt died. She started a relationship with boyfriend Alberto Figueroa in 2011.
Miss Venezuela 2012
Isler, who stands 1.79 m (5 ft 10 in), competed as Miss Gu�rico, one of 24 finalists in her country's national beauty pageant Miss Venezuela 2012, held on August 30, 2012 in Caracas, where she obtained the Miss Elegance award and became the ninth Miss Venezuela winner from Guarico, gaining the right to represent her country in Miss Universe.
Miss Universe 2013
Isler represented Venezuela at the Miss Universe 2013 pageant, held on November 9 in Moscow, Russia. She was crowned Miss Universe 2013 by outgoing titleholder, Olivia Culpo of the USA. Isler became the third Venezuelan to win the pageant in six years (since 2008) and the seventh overall, maintaining its status as the second most successful entity at Miss Universe.
Reign as Miss Universe
After being crowned on November 9, 2013 in Moscow, Isler was interviewed by CNN en Espanol; Fox News; EFE agency (Spain); the Associated Press; Reuters; Venevision and Globovision (Venezuela); Caracol Television (Colombia); 2M TV (Morocco); ABS-CBN (Philippines); MUN2; Pust Gorovyat and Evening Urgant (Russia); Rendezvous Indosiar (Indonesia); NBC's Today, Fox & Friends, Huffpost Live, Live with Kelly and Michael, PIX11 Morning News, Good Day NY; Al Rojo Vivo; Un Nuevo D�a, Titulares yk Mas and Acceso Total (Telemundo); The Lab;Fashion Files (Mexico Travel Channel) and others.On November 10, 2013, Isler participated in the presentation of the Yamamay Million dollar swimsuit at Crowne Plaza hotel in Moscow, Russia.
On November 21, 2013, she served as a presenter at the Latin Grammy Awards in Las Vegas, United States, sharing with Illya Kuryaki and the Valderramas.A few days later she traveled to Asheville, North Carolina.On December 2, 2013, she attended The Man With Opera Hat in New York City. Isler attended Elizabeth Glaser Pediatric AIDS Foundation's Global Impact award Gala Dinner honoring Hillary Clinton at Best Buy Theater on December 3, 2013 in New York City. On December 4, 2013 she attended the 81st annual Rockefeller Center Christmas Tree Lighting Ceremony at Rockefeller Center in New York City. On December 11, 2013, Isler traveled to Venezuela on an unofficial visit to enjoy Christmas with her family. She traveled to Bali, Indonesia on January 7, 2014, where she filmed a publicity for YOU�C1000.